Unless otherwise indicated or the context otherwise requires, references in this
report (this "Quarterly Report") to "we," "our," "us," "UpHealth" or the
"Company" and other similar terms refer to UpHealth, Inc. and its consolidated
subsidiaries. The following discussion and analysis of our financial condition
and results of operations should be read in conjunction with our unaudited
condensed consolidated financial statements and the notes thereto contained
elsewhere in this Quarterly Report. Certain information contained in the
discussion and analysis set forth below includes forward-looking statements that
involve risks and uncertainties.

Special Note Regarding Forward-Looking Statements


This Quarterly Report includes "forward-looking statements" within the meaning
of Section 27A of the Securities Act of 1933 and Section 21E of the Exchange Act
that are not historical facts, and involve risks and uncertainties that could
cause actual results to differ materially from those expected and projected. All
statements, other than statements of historical fact included in this Quarterly
Report including, without limitation, statements in this "Management's
Discussion and Analysis of Financial Condition and Results of Operations"
regarding the company's financial position, business strategy and the plans and
objectives of management for future operations, are forward-looking statements.
Words such as "expect," "believe," "anticipate," "intend," "estimate," "seek,"
"may," "might," "plan," "possible," "potential," "should, "would" and similar
words and expressions are intended to identify such forward-looking statements.
Such forward-looking statements relate to future events or future performance,
but reflect management's current beliefs, based on information currently
available. A number of factors could cause actual events, performance or results
to differ materially from the events, performance and results discussed in the
forward-looking statements. For information identifying important factors that
could cause actual results to differ materially from those anticipated in the
forward-looking statements, please refer to the "Risk Factors" section in Part
II Item 1A. of this in this Quarterly Report, the "Risk Factors" section in our
Annual Report on Form 10-K for the fiscal year ended December 31, 2021 filed
with the SEC on April 18, 2022 (our "Annual Report") and in any more recent
filings with the SEC. The company's securities filings can be accessed on the
EDGAR section of the SEC's website at www.sec.gov. Except as expressly required
by applicable securities law, the company disclaims any intention or obligation
to update or revise any forward-looking statements whether as a result of new
information, future events or otherwise.

UpHealth, Inc. Business Overview


UpHealth Services, Inc. was formed on November 5, 2019, and effectively began
operations on January 1, 2020. It was formed for the purpose of effecting a
combination of various companies engaged in digital health, and commenced
negotiations with a number of companies, including those that are discussed
below as having been acquired. UpHealth Holdings, Inc. ("UpHealth Holdings")
became the sole shareholder of UpHealth Services, Inc. through a reorganization
with UpHealth Services, Inc.'s original shareholders when UpHealth Holdings was
formed on October 26, 2020 as a Delaware corporation. UpHealth Holdings then
entered into a series of transactions to develop its business across three
segments: (a) Integrated Care Management-through its subsidiary Thrasys, Inc.
("Thrasys"); (b)Virtual Care Infrastructure-through its subsidiary Glocal
Healthcare Systems Private Limited ("Glocal"); and (c) Services-through its
subsidiaries Innovations Group, Inc. ("Innovations Group"), Behavioral Health
Services, LLC ("BHS") and TTC Healthcare, Inc. ("TTC"). On June 9, 2021,
UpHealth (fka GigCapital2, Inc.) acquired UpHealth Holdings and its subsidiaries
and Cloudbreak Health, LLC and its subsidiaries ("Cloudbreak"), which added
Cloudbreak to the Virtual Care Infrastructure segment.

As a result of events which occurred during the three months ended September 30,
2022, as described in Dispute and Litigation Regarding Control of Glocal Board
of Directors of Item 1. Legal Proceedings in Part II of this Quarterly Report,
we determined that a reconsideration event occurred in July 2022, which required
us to reassess whether Glocal was a Variable Interest Entity ("VIE") and whether
we continued to have a controlling financial interest in Glocal Healthcare
Systems Private Limited ("Glocal"). Based on this assessment, we concluded that
Glocal was a VIE, and furthermore, that we no longer have the ability to direct
any activities of Glocal and no longer have a controlling financial interest. As
a result, effective July 2022, we deconsolidated Glocal and recorded a
$37.7 million loss on deconsolidation of equity investment in our unaudited
condensed consolidated statements of operations, measured as the difference
between the probability-weighted fair value of Glocal of $21.2 million and the
carrying amount of Glocal's assets and liabilities as of June 30, 2022. The
probability-weighted fair value of Glocal is included in equity investment in
our unaudited condensed consolidated balance sheets. Further, we assessed the
prospective accounting for our equity investment in Glocal. Since we no longer
had the ability to exercise significant influence over operating and financial
policies of Glocal, we concluded the investment should be accounted for
utilizing the ASC 621 measurement alternative, whereby the investment was
measured at cost and will continue to be evaluated for any indicators of
impairment. In addition, we derecognized $14.3 million of noncontrolling
interests related to Glocal. If through the legal processes discussed in Dispute
and Litigation Regarding Control of Glocal Board of Directors of Item 1. Legal
Proceedings in Part II of this Quarterly Report, we are able to obtain the
ability to direct the activities of Glocal, and it is our intent to exercise all
legal rights and remedies to achieve such a result, then we will further
reassess the appropriate accounting treatment of our investment in Glocal.

Integrated Care Management Segment – Thrasys

Thrasys Overview

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Thrasys provides its customers with an advanced, comprehensive, and extensible
technology platform, marketed under the umbrella "SyntraNetTM," to manage
health, quality of care, and costs, especially for individuals with complex
medical, behavioral health, and social needs. Thrasys focuses on both the United
States and international markets. SyntraNetTM is offered as a
software-as-a-service ("SaaS") platform. Information, analytics, and
applications are delivered to care team members on desktops, tablets, and
phones, as needed. An advanced protected health information ("PHI") framework
controls access to information based on roles, rights, policies, and scope of
consent. The platform includes innovations in a number of areas: application and
information models for connected care communities (an extension of multi-tenant
architectures), integration and normalization of heterogeneous data sources,
configurable software services and open application programming interfaces
("APIs"), advanced analytics and intelligence, scalable workflows and rules,
protected health information management, and user interfaces ready for the
proliferation of device types and interaction modes.

Thrasys Key Business Metrics

Revenues


Thrasys derives revenues broadly through technology licenses and subscriptions
revenues, including hosting fees, and services provided to implement, configure,
and extend the technology, and train and on-board users on the use of the
platform and applications.

Licenses and Subscriptions. License revenues are typically associated with
rights granted to customers to deploy the platform to a certain number of care
communities of a certain size, usually measured as the total population of
patients that can be included within a care community. License revenues are
recognized based on the nature of the license provided, either fully on the date
license rights are granted to the customer if there are no further performance
obligations or ratably over the license term beginning on the effective date of
each contract, the date the customer takes possession of the license rights.

Subscription revenues are recurring fees charged for access to the platform and
applications. Subscription fees are typically pegged to a measure of use, such
as population size, number of providers, members enrolled in programs, or number
of members managed by applications. Subscription fees can grow as customers
subscribe to additional application features or launch additional programs.
Revenues from subscription fees are recognized ratably over the subscription
term.

Services. The majority of Thrasys' contracts to provide professional services
are priced either on a time and materials basis, whereby revenues are recognized
as the services are rendered, or as a fixed monthly retainer based on an
estimate of the number of hours of work over the contract term, whereby revenues
are recognized on a straight-line basis over the contract term. In some cases,
Thrasys enters into professional services contracts where professional services
fees are defined for specific milestones, whereby revenues are recognized upon
achievement of the milestones.

Cost of Revenues


Cost of revenues for Thrasys include: costs related to hosting SyntraNetTM in a
HIPAA-compliant cloud environment, costs of third-party product licenses
embedded with SyntraNetTM, costs of a core professional services team,
amortization of capitalized internal-use software development costs, and an
allocation of facilities, information technology, and depreciation costs. Added
compliance requirements for security infrastructure is likely to add some
additional costs for hosting services. Thrasys also anticipates added costs for
third-party licenses that will be added as the scope and footprint of the
technology platform expands.

Hosting Infrastructure. Thrasys' technology and solutions are designed to be
agnostic to any particular cloud services provider. Currently, customer
environments are hosted through contracts with two cloud service providers.
Thrasys anticipates capabilities of cloud service providers to grow, and costs
to become increasingly competitive, and will continue to evaluate offerings in
the marketplace to determine the optimum mix of security, reliability,
scalability, and performance to meet customer needs. Hosting infrastructure
costs for Thrasys are related to the number and size of environments deployed
for customers and also on the service level agreements ("SLAs") negotiated with
customers. As the average size of customers continues to grow, hosting
infrastructure costs are expected to grow as a percentage of revenues.

Third-Party Product Licenses. SyntraNetTM embeds certain third-party technology
components to support some of its technology capabilities. There are multiple
vendors for these components, and Thrasys is not dependent on any specific
vendor.

Professional Services Team. Thrasys' professional services team works closely
with the product team and is best understood as an "A-team" created to lead
showcase implementations. The goal is to keep the professional services team
small in order to focus it on deploying reference customers and facilitating the
on-boarding and coaching of systems integration partners.

Operating Expenses
Sales and Marketing ("S&M") Expenses. S&M expenses include an internal sales and
marketing team and contracts with business development consultants to generate
and qualify leads, and an allocation of facilities, information technology, and
depreciation costs.

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Research and Development ("R&D") Expenses. Thrasys continues to invest in R&D.
The core R&D team consists of a small team of very experienced software
developers. Beginning in 2019, Thrasys added considerable capacity via a
consulting group with whom it has been working for over ten years. The team,
based in Chicago, functioned much like the Thrasys internal team, until they
were brought in-house in June 2021. R&D expenses attributed to internal-use
software development are capitalized and amortized to cost of revenues. R&D
expenses also include an allocation of facilities, information technology, and
depreciation costs.

General and Administrative ("G&A") Expenses. G&A expenses include compensation
and benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues, S&M expenses and R&D expenses.

Depreciation and Amortization Expenses. Depreciation expense relates to the
depreciation of computer equipment, purchased software, furniture and fixtures,
and office equipment, net of amounts allocated to cost of revenues. Amortization
expense relates to the amortization of intangible assets from the acquisition of
Thrasys.

Virtual Care Infrastructure Segment – Cloudbreak and Glocal

Cloudbreak Overview


Cloudbreak is a leading provider of unified telemedicine solutions and digital
health tools aimed at increasing access to healthcare and resolving health
disparities across the care continuum, at each stage of healthcare acuity.
Cloudbreak powers its client's healthcare digital transformation initiatives and
provides digital health infrastructure enabling its partners to address
healthcare disparities and implement unique, private-label, telehealth
strategies customized to their specific needs and markets.

Cloudbreak's core offering, known as Martti™, is a video remote interpreting
solution that puts qualified and certified medical interpreters at the
fingertips of clinical care teams nationwide through Cloudbreak's proprietary
software platform. Having one of the largest installed bases of video endpoints
in the nation, Cloudbreak has expanded its operations to include other
telemedicine use cases as well, including tele-stroke, tele-psychiatry,
tele-urology, and tele-quarantine, among others, all over the same
infrastructure. Cloudbreak has also recently launched a home health virtual
visit platform enabling its healthcare system partners to see their patients
remotely on any device, at anytime, anywhere the patient may be, and in any
language they may speak. Cloudbreak's client base spans the entire healthcare
continuum including hospitals and health systems, Federally Qualified Healthcare
Centers, urgent care centers, stand-alone clinics and medical practices,
employers, and schools.

Cloudbreak's Telemedicine-as-a-Service ("TaaS") business model aligns interests
between Cloudbreak and its clients, creating a partnership targeted towards
forming long-term agreements with sustainable and mutually beneficial growth
models for all stakeholders. Cloudbreak has specifically structured itself to
not have a captive medical group as it believes that creates a conflict of
interest with its client base, as local health systems do not want to suffer
patient leakage to a technology partner or be forced to use a provider network.
As a result, Cloudbreak has the freedom to match its partners with centers of
excellence on its network, who can satisfy their specific needs and strategy
without fear of competing for the patient's attention, and thereby avoid the
employment and maintenance of a medical group, which is a lower margin and a
more labor intensive activity.

Cloudbreak Key Business Metrics

Revenues


Services. Services revenues are generated primarily from the sale of
subscription-based fixed monthly minute and variable rate per unit of service
medical language interpretation services. Cloudbreak also records ancillary
revenues from the rental of Martti™ devices and from the provision of
information technology services that include connectivity and ongoing support of
the Martti™ software platform. Generally, Cloudbreak's medical language
interpretation and information technology services are invoiced monthly. Fixed
monthly minute medical language interpretation subscription and information
technology services fees are invoiced in advance in the period preceding the
service. Variable rate per unit medical language interpretation and information
technology services fees (including overage fees related to minutes used by the
customer in excess of the fixed monthly minute subscription) are invoiced
monthly in arrears. Martti™ device leases are invoiced monthly in advance in the
period preceding the usage. Invoiced amounts are typically due within 30 days of
the invoice date.

Products. Products revenues consist of the sale of Martti™ devices to its
customers. Sale of Martti™ devices are generally invoiced at contract execution
(50%) and upon the delivery of the devices to the customer (50%). Invoiced
amounts are typically due within 30 days of the invoice date.

Cost of Revenues

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Cost of revenues primarily consist of costs related to supporting and hosting
Cloudbreak's product offerings and delivering services, and include the cost of
maintaining Cloudbreak's data centers, customer support team, and Cloudbreak's
professional services staff, in addition to third-party service provider costs
such as data center and networking expenses, amortization of capitalized
internal-use software development costs, the cost of purchased equipment
inventory sold to customers, and an allocation of facilities, information
technology, and depreciation costs.

Operating Expenses


Sales and Marketing Expenses. S&M expenses consist of costs related to
advertising, marketing programs, and events including related wages, commissions
and travel expenses, and an allocation of facilities, information technology,
and depreciation costs.

General and Administrative Expenses. G&A expenses consist of compensation and
benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues and S&M.

Depreciation and Amortization Expenses. Depreciation expense relates to the
depreciation of computer equipment, purchased software, furniture and fixtures,
and office equipment, net of amounts allocated to cost of revenues. Amortization
expense relates to the amortization of intangible assets from the acquisition of
Cloudbreak.

Glocal Overview

As discussed in Note 1, Organization and Business, in the Notes to Condensed
Consolidated Financial Statements of this Quarterly Report, we deconsolidated
Glocal during the three months ended September 30, 2022; therefore, the
financial results of Glocal as of December 31, 2021 and for the three months
ended September 30, 2021, the period from March 26, 2021 to September 30, 2021,
and the period from January 1, 2022 to June 30, 2022 are included in our
unaudited condensed consolidated financial statements, and the financial results
of Glocal as of September 30, 2022 and for the three months then ended are not
included in our unaudited condensed consolidated financial statements.

Glocal is a technology and process-based healthcare platform providing its
customer comprehensive primary care and specialty consultations for a fraction
of the cost of traditional healthcare delivery systems, through telemedicine,
digital dispensaries, and technology-based hospital centers. Glocal has been
awarded by the United Nation's ("UN") Innovation Exchange with the Public
Appreciation Award 2020 as a cutting-edge technology to meet the sustainable
development goals of the UN.

Glocal pioneered the development of a semantic algorithm and AI-based clinical
decision support system called LitmusDX, which helps deliver healthcare through
telemedicine in its HelloLyf CX digital dispensaries and HelloLyf HX digital
hospital, utilizing a telemedicine terminal called LitmusMX and an automated
medicine dispenser called LitmusRX.

LitmusMX is used for recording the vitals of the patient, consultations with a
doctor over video conferencing from miles away, and routine card-based
point-of-care tests, and also contains a fully automatic biochemistry analyzer.
The software may also suggest further investigations. If the doctor agrees, they
can order further rapid tests, such as for dengue or malaria, for which kits are
available. When the doctor selects a prescription, LitmusMX talks to the
LitmusRX automated medicine dispensing unit, which delivers the required dosages
of the medicines. Theoretically, the algorithm can be fine-tuned to arrive at a
final diagnosis and prescription on its own. In addition to these solutions is
one of the world's top end-to-end Clinical Decision Support System ("CDSS"),
named LitmusDX, along with a web interface, named HelloLyf, which integrates
practice management with diagnostic algorithms, investigation interpretation,
treatment protocols, drug safety checks, and electronic medical records.

Glocal's HelloLyf CX digital dispensary was selected by United Nations AID as a
cutting-edge technology solution to reach the UN's sustainable development
goals. Unlike other telemedicine centers seen today, Glocal's HelloLyf CX
digital dispensary is an innovative, hybrid, brick-and-mortar center, which
provides complete primary and emergency healthcare solutions, such as
consultation, confirmatory tests, and medicines, from a single point through the
use of LitmusMX and LitmusRX. During the COVID-19 pandemic, Glocal's innovative
HelloLyf CX digital dispensaries successfully used ultraviolet C light
disinfection, acrylic separation, and positive air pressure to create the first
line for defense of health workers and patients against all forms of infectious
and contagious diseases, including COVID-19.

In September 2021, Glocal delivered its first digital hospital in the Indian
state of Nagaland, providing 88 e-ICU beds with connected ventilators and
injection syringe pump. This digital hospital utilizes Glocal's HelloLyf patient
management, digital health, and decision support software to provide and
coordinate outpatient care, emergency care, radiology and imaging, intensive
care, high-dependency care, inpatient care, and dialysis.

While Glocal's customers are located in regions in India and Southeast Asia,
Glocal generates the majority of its revenues in India. Glocal's
telemedicine/HelloLyf CX digital dispensaries have been functional in India
mainly through the government and are primarily housed in government facilities,
which provide services that are free to the beneficiaries. After successful
implementation of projects in the Indian states
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of Rajasthan, Odisha, and West Bengal, Glocal won a contract to set-up 550+
HelloLyf CX digital dispensaries in the Indian State of Madhya Pradesh,
resulting in a total of 750+ government-placed nodes across India.


Glocal has begun focusing on a business-to-business ("B2B") model where the
HelloLyf CX digital dispensaries are sold to B2B partners/customers, who operate
them with a revenue-share to Glocal. This results in lower revenues but higher
margins.

Glocal also owns nine hospitals, four of which it operates and five of which it
has contracted with third parties to operate with Glocal receiving a
revenue-share.


Glocal Key Business Metrics

Revenues

Services. Services revenues are generated primarily from operating hospitals and
clinics, including pharmacy and medicine sales, and transaction fees per
telemedicine consultation.

Products. Products revenues are generated primarily from the sale of HelloLyf CX
digital dispensaries and the construction of HelloLyf HX digital hospitals.

Cost of Revenues


Cost of revenues primarily consist of costs of building and operating hospitals,
including costs for the purchase of medicines, professional/doctor fees, the
cost to build HelloLyf CX digital dispensaries and HelloLyf HX digital
hospitals, and an allocation of information technology and depreciation costs.

Operating Expenses


Sales and Marketing Expenses. S&M expenses are comprised of compensation and
benefits related to Glocal's sales personnel, travel expenses, and expenses
related to advertising, marketing programs, and events, and an allocation of
facilities, information technology, and depreciation costs.

General and Administrative Expenses. G&A expenses include compensation and
benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues and S&M expenses.

Depreciation and Amortization Expenses. Glocal’s operations are capital
intensive. Depreciation expense relates to the depreciation of buildings,
computer equipment, purchased software, furniture and fixtures, and office
equipment, net of amounts allocated to cost of revenues. Amortization expense
relates to the amortization of intangible assets from the acquisition of Glocal.

Services Segment – Innovations Group, TTC and BHS

Innovations Group Overview


Innovations Group is the parent company of the following wholly-owned operating
subsidiaries: MedQuest Pharmacy, Inc. ("MedQuest Pharmacy"), WorldLink Medical,
Inc ("WorldLink Medical"), Medical Horizons, Inc. ("Medical Horizons"), and
Pinnacle Labs, Inc. (doing business as MedQuest Testing Services ("MTS")).

MedQuest Pharmacy is a full-service compounding pharmacy licensed in 50 states
and the District of Columbia that has relationships with both prescribers and
patients, dispenses patient-specific medications, and ships directly to
patients. The business model is driven by cash-pay and prescription volume-based
revenues generated by physician electronic prescription order entry, as well as
traditional prescriber-patient-pharmacist interactions, mailed, verbal, and
faxed orders. It delivers both compounded and legend (also referred to as
manufactured) drugs and is capable of serving as a mail order or national
fulfillment center, as a personalized medication administration partner with
prescribers, and as a lifestyle wellness direct-to-consumer offering. Its
proprietary software and operating system, eMedplus, is Electronic Prescribing
of Controlled Substances ("EPCS") certified by the U.S. Drug Enforcement
Administration ("DEA") and provides prescribers with a full-service prescription
management system. In January 2020, eMedplus became SureScripts certified
(SureScript's process is to validate that the software meets certain industry
standards related to sending and receiving electronic messages and that it is
providing open choice for medication selection and dispensing location),
allowing any user of the SureScripts platform to prescribe medications dispensed
by MedQuest Pharmacy.

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MedQuest Pharmacy is accredited and recognized by the Accreditation Commission
for Health Care and its Pharmacy Compounding Accreditation Board, among other
high-quality providers and suppliers. MedQuest Pharmacy has achieved this elite
level of quality by exceeding standards set by national accreditation bodies and
quality-centered organizations.

MedQuest Pharmacy is currently working on expanding its prescriber base, through
both current prescribers and new prescribers, through marketing efforts and
training via the Worldlink education conferences. Medical Horizons (product
brand is NutraScriptives) is also expanding their sales of supplements through
the new products like Nutra Direct and Nutra referral programs, which allows
physicians to profit from referrals and direct recommendations of Nutra
supplements.

Also under the Innovations Group suite of services is WorldLink Medical, which
is also known as "The Academy of Preventative and Innovative Medicine," Medical
Horizons, and MedQuest Testing Services. WorldLink Medical is the educational
services arm of Innovations Group, providing Continuing Medical Education
("CME") educational courses accredited as a joint provider through the
Accreditation Council for Continuing Medical Education ("ACCME"). Medical
Horizons specializes in customized formulations and contract dietary supplement
and nutraceuticals manufacturing as an own label distributor with its brand
NUTRAscriptivesTM, as well as other brands. Its turnkey solutions include label
design, printing, and application; custom packaging; daily packs; a selection of
capsule sizes and colors; and convenient auto-reorder services. It features a
staff of experts that is committed to excellence and outstanding customer
service. MedQuest Testing Services focuses specifically on facilitating
diagnostic testing between lab companies, such as LabCorp and Quest Diagnostics,
patients, and providers.

Innovations Group Key Business Metrics

Revenues


Products. Products revenues are generated primarily from the sale of
prescription medications directly to patients, as well as through the sale of
supplemental products to providers and patients. The majority of customer
revenues are billed and collected before the medications and products are
shipped from the facility. MedQuest Pharmacy is Innovation's largest subsidiary
in terms of revenues and generates approximately 60% of its revenues from sales
of compounded medications and approximately 40% of its revenues from sales of
manufactured medications and supplements.

Services. Services revenues are generated primarily from CME educational courses
provided by WorldLink Medical and MedQuest Testing, with the majority coming
from WorldLink.

Cost of Revenues

Cost of revenues primarily consist of costs of raw ingredients and materials to
compound various drugs and supplements, the cost of manufactured product
purchased directly from the distributors for resale, the cost of fulfillment and
shipping services, amortization of capitalized internal-use software development
costs, and an allocation of facilities, information technology, and depreciation
costs. MedQuest Pharmacy purchases these items through a large industry
distributor with many suppliers and also sources products and supplies directly
with manufacturers. MedQuest Pharmacy is also able to leverage the size of its
operations to purchase larger quantities of certain ingredients and materials at
lower prices.

Operating Expenses

Sales and Marketing Expenses. S&M expenses consist of costs related to
advertising, marketing programs, and events including related wages, commissions
and travel expenses, and an allocation of facilities, information technology,
and depreciation costs.

General and Administrative Expenses. G&A expenses include compensation and
benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues and S&M expenses.


Depreciation and Amortization Expenses. Depreciation expense relates to the
depreciation of computer equipment, lab equipment, purchased software, furniture
and fixtures, office equipment, and leasehold improvements, net of amounts
allocated to cost of revenues. Amortization expense relates to the amortization
of intangible assets from the acquisition of Innovations Group.

TTC Overview


TTC provides inpatient and outpatient mental health and substance abuse
treatment services for individuals with behavioral health issues, including
post-traumatic stress disorder and drug and alcohol addiction. TTC offers a
complete continuum of care from its detoxification services, residential care,
partial hospitalization programs, and intensive outpatient, and outpatient
programs. During the COVID-19 pandemic, outpatient programs have been virtual
for a majority of visits.
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In March 2020, TTC formed Transformations Mending Fences, LLC to provide mental
health and substance abuse disorder treatment, including equine therapy, to
patients. TTC has an 80% controlling interest in the entity with the remaining
20% interest owned by an unrelated party. Operations began in December 2020,
with the admission of the first patient occurring in January 2021.

In addition to inpatient and outpatient substance abuse treatment services, TTC
performs screenings, urinalysis, and diagnostic laboratory services, and
provides physician services to clients. TTC operates three subsidiaries located
in Delray Beach, Florida and one facility in Morriston, Florida. These
facilities consist of inpatient substance abuse treatment facilities, standalone
outpatient centers, and sober living facilities focused on delivering effective
clinical care and treatment solutions.

TTC Key Business Metrics

Revenues


Services. TTC generates revenues primarily through services provided to clients
in both inpatient and outpatient treatment settings. TTC bills third-party
payors weekly for the services provided in the prior week. Client-related
services, such as inpatient and outpatient programs, are generally recognized
over time as the performance obligation is satisfied at the estimated net
realizable value amount from clients, third-party payors, and others for
services provided. TTC receives the majority of payments from commercial payors
at out-of-network rates. Client service revenues are recorded at established
billing rates, less adjustments to estimate net realizable value. Provisions for
estimated third party payor reimbursements are provided in the period related
services are rendered and adjusted in future periods when actual reimbursements
are received. A significant or sustained decrease in reimbursement rates could
have a material adverse effect on operating results.

TTC provides diagnostic laboratory testing services for its clients, which are
recognized over time as the performance obligation is satisfied at the estimated
net realizable value amount from clients, third-party payors, and others for
services provided. Diagnostic laboratory service revenues are recorded at
established billing rates, less adjustments to estimate net realizable value.
Provisions for estimated third party payor reimbursements are provided in the
period related services are rendered and adjusted in future periods when actual
reimbursements are received.

Cost of Revenues

Cost of revenues primarily consist of the costs of operating the facilities,
professional/doctor fees, and an allocation of information technology and
depreciation costs.

Operating Expenses

Sales and Marketing Expenses. S&M expenses consist of costs related to
advertising, marketing programs, and events.

General and Administrative Expenses. G&A expenses include compensation and
benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues and S&M expenses.


Depreciation and Amortization Expenses. Depreciation expense relates to the
depreciation of computer equipment, purchased software, furniture and fixtures,
office equipment, and leasehold improvements, net of amounts allocated to cost
of revenues. Amortization expense relates to the amortization of intangible
assets from the acquisition of TTC.

BHS Overview


BHS operates through Psych Care Consultants, LLC, BHS Pharmacy, LLC, and
Reimbursement Solutions, LLC, wholly-owned subsidiaries of BHS. Psych Care
Consultants, LLC is a medical group that has three medical offices located in
the St. Louis Metropolitan area (Missouri) and provides psychiatric and mental
health services. BHS Pharmacy, LLC provides retail pharmacy services
specializing in behavioral health through services, such as medication
management, screenings, online portals, and delivery. Reimbursement Solutions,
LLC provides billing services for Psych Care Consultants, LLC (which has allowed
for more efficient payment for BHS clinicians) and third-party customers.
Services include billings, collections, verification of benefits, authorization,
and credentialing.

BHS provides its patients and providers with a reliable platform where a
provider can address their patients' needs efficiently with an infrastructure
built to support the providers and address patient needs. This infrastructure
consists of medical offices placed strategically for the convenience of
providers and patients and trained staff to assist providers and patients in the
delivery of quality health services that is timely and efficient, provide
prescription dispensing for patients that is convenient to maintain compliance,
and assist providers with billing and collection services through Reimbursement
Solutions, LLC.

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BHS providers work in collaboration with multiple area hospital systems (both in
leadership and clinical positions) to provide and direct inpatient treatment.
BHS' business is generated by various referral sources developed over the years
by BHS' providers and their presence in the market for over twenty-five years.
BHS offers in-office, virtual, and in-patient treatment. Common conditions
treated by BHS practitioners include depression, bipolar disorder, attention
disorders, schizophrenia, substance use disorders, post-traumatic stress
disorder, Alzheimer's disease and related disorders, and personality disorders.

BHS Key Business Metrics

Revenues

Services. Services revenues are generated primarily by providing psychiatric and
mental health services and billing services. Although the underlying tasks will
vary by service and by patient, medical professionals perform inquiries, obtain
vital statistics, perform certain lab tests, administer therapy, and provide any
additional goods and services as necessary depending on the information
obtained.

Products. Products revenues are generated primarily by providing retail pharmacy
services through BHS Pharmacy, LLC.

Cost of Revenues


Cost of revenues consist primarily of provider compensation expenses, the cost
of pharmaceutical medications sold to patients, and an allocation of facilities,
information technology, and depreciation costs. Provider compensation expenses
include consulting payments to BHS' healthcare providers, including medical
doctors in psychiatry, psychologists, nurse practitioners, and clinical social
workers. BHS has adopted an incentive-based compensation plan with provider
agreements that compensate the providers based upon a percentage of revenues
generated and ultimately collected for services provided. BHS primarily
purchases pharmaceutical medications through a large industry distributor with
many suppliers, but also purchases some directly from other suppliers.

Operating Expenses

General and Administrative Expenses. G&A expenses include compensation and
benefits expense, and other administrative costs, related to its executive,
finance, human resources, legal, facilities, and information technology teams,
net of allocations to cost of revenues.

Depreciation Expense. Depreciation expense relates to the depreciation of
computer equipment, purchased software, furniture and fixtures, and office
equipment, net of amounts allocated to cost of revenues. Amortization expense
relates to the amortization of intangible assets from the acquisition of BHS.

Critical Accounting Policies


The preparation of financial statements and related disclosures in conformity
with accounting principles generally accepted in the United States of America
("GAAP") requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities, disclosure of contingent assets and
liabilities at the date of the financial statements, and income and expenses
during the periods reported. These estimates and assumptions are based on
current facts, historical experience, and various other factors that we believe
are reasonable under the circumstances to determine reported amounts of assets,
liabilities, revenues and expenses that are not readily apparent from other
sources. To the extent there are material differences between our estimates and
the actual results, our future consolidated results of comprehensive income
(loss) may be affected.

Among our significant accounting policies, which are described in Note 2,
Summary of Significant Accounting Policies, in the Notes to Condensed
Consolidated Financial Statements of this Quarterly Report, as well as Note 2,
Summary of Significant Accounting Policies, in the Notes to Consolidated
Financial Statements for the year ended December 31, 2021 included in our Annual
Report, the following accounting policies and specific estimates involve a
greater degree of judgment and complexity:

•Business combinations;

•Identification and reporting of variable interest entities (“VIEs”);

•Goodwill and intangible assets;

•Revenue recognition;

•Capitalized software;

•Valuation of derivatives and warrants; and

•Income taxes.

Identification and Reporting of Variable Interest Entities (“VIE”)

                                       42
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When analyzing whether an entity is a VIE, we assess if (1) the equity is
sufficient to finance the entity's activities without additional subordinated
financial support, (2) the equity holders have the right to make significant
decisions affecting the entity's operations, and (3) the holders of the voting
rights substantively participate in the gains and losses of the entity. When one
of these criteria is not met, the entity is considered a VIE and is assessed for
consolidation.

The party that has a controlling financial interest is called a primary
beneficiary and consolidates the VIE. The party is deemed to have a controlling
financial interest if it has both:

•The power to direct the activities of the VIE that most significantly impact
the entity’s economic performance; and

•The obligation to absorb the entity’s losses that could potentially be
significant to the VIE or the right to receive benefits from the entity that
could potentially be significant to the VIE.


We assess whether we have a controlling financial interest in an entity and,
thus, are the primary beneficiary. We identify the activities that most
significantly impact the entity's performance and determine whether we have the
power to direct those activities. In conducting the analysis, we consider the
purpose, the design, and the risks that the entity was designed to create and
pass through to its variable interest holders. Additionally, we assess if we
have the obligation to absorb losses or if we have the right to receive benefits
of the VIE that could potentially be significant to the entity. If both criteria
are met, we have a controlling financial interest in the VIE and consolidate the
entity. We monitor changes to the facts and circumstances of the existing
involvement with legal entity to determine whether it requires reconsideration
of the entity's designation as a VIE or voting interest entity. For VIEs, we
regularly reassess the primary beneficiary determination.

As a result of events which occurred during the three months ended September 30,
2022, as described in Dispute and Litigation Regarding Control of Glocal Board
of Directors of Item 1. Legal Proceedings in Part II of this Quarterly Report,
we determined that a reconsideration event occurred in July 2022, which required
us to reassess whether Glocal was a VIE and whether we continued to have a
controlling financial interest in Glocal. Based on this assessment, we concluded
that Glocal was a VIE, and furthermore, that we no longer have the ability to
direct any activities of Glocal and no longer have a controlling financial
interest. As a result, effective July 2022, we deconsolidated Glocal and
recorded a $37.7 million loss on deconsolidation of equity investment in our
unaudited condensed consolidated statements of operations, measured as the
difference between the probability-weighted fair value of Glocal of
$21.2 million and the carrying amount of Glocal's assets and liabilities as of
June 30, 2022. The probability-weighted fair value of Glocal is included in
equity investment in our unaudited condensed consolidated balance sheets.
Further, we assessed the prospective accounting for our equity investment in
Glocal. Since we no longer had the ability to exercise significant influence
over operating and financial policies of Glocal, we concluded the investment
should be accounted for utilizing the ASC 621 measurement alternative, whereby
the investment was measured at cost and will continue to be evaluated for any
indicators of impairment. In addition, we derecognized $14.3 million of
noncontrolling interests related to Glocal. If through the legal processes
discussed in Dispute and Litigation Regarding Control of Glocal Board of
Directors of Item 1. Legal Proceedings in Part II of this Quarterly Report, we
are able to obtain the ability to direct the activities of Glocal, and it is our
intent to exercise all legal rights and remedies to achieve such a result, then
we will further reassess the appropriate accounting treatment of our investment
in Glocal.

The financial results of Glocal as of December 31, 2021 and for the three months
ended September 30, 2021, the period from March 26, 2021 to September 30, 2021,
and the period from January 1, 2022 to June 30, 2022 are included in our
unaudited condensed consolidated financial statements, and the financial results
of Glocal as of September 30, 2022 and for the three months then ended are not
included in our unaudited condensed consolidated financial statements. There are
no transactions between the Company and Glocal during the three months ended
September 30, 2022.

Aside from the Glocal deconsolidation, there have been no changes to our
critical accounting policies and estimates described in our Annual Report that
have had a significant impact on our unaudited condensed consolidated financial
statements and related notes.

UpHealth, Inc. Consolidated Results of Operations

Operating Results


As discussed in Note 1, Organization and Business, in the Notes to Condensed
Consolidated Financial Statements of this Quarterly Report, we deconsolidated
Glocal during the three months ended September 30, 2022; therefore, the
financial results of Glocal as of December 31, 2021 and for the three months
ended September 30, 2021, the period from March 26, 2021 to September 30, 2021,
and the period from January 1, 2022 to June 30, 2022 are included in our
unaudited condensed consolidated financial statements, and the financial results
of Glocal as of September 30, 2022 and for the three months then ended are not
included in our unaudited condensed consolidated financial statements.

As of September 30, 2021 and for the three and nine months then ended,
UpHealth’s operating results consist of the results of operations for UpHealth
and its subsidiaries Thrasys, BHS, TTC, Glocal, Innovations Group, and
Cloudbreak.


As of September 30, 2022 and for the three months then ended, UpHealth's
operating results consist of the results of operations for UpHealth and its
subsidiaries Thrasys, BHS, TTC, Innovations Group, and Cloudbreak, and for the
nine months then ended, UpHealth's operating results consist of the results of
operations for UpHealth and its subsidiaries Thrasys, BHS, TTC, Innovations
Group, and Cloudbreak for the entire period, and the result of operations for
Glocal for the period from January 1, 2022 to June 30, 2022.
                                       43
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The following table sets forth the consolidated results of operations of
UpHealth:


(Unaudited, in thousands)            Three Months Ended September 30,                                                 Nine Months Ended September 30,
                                          2022               2021             $ Change             % Change                2022               2021             $ Change             % Change
Revenues:
Services                             $    27,600          $ 21,977          $    5,623                    26  %       $    81,382          $ 45,563          $   35,819                    79  %
Licenses and subscriptions                 2,019            10,956              (8,937)                  (82) %            10,612            23,759             (13,147)                  (55) %
Products                                   9,047            12,259              (3,212)                  (26) %            26,312            20,568               5,744                    28  %
Total revenues                            38,666            45,192              (6,526)                  (14) %           118,306            89,890              28,416                    32  %
Costs of revenues:
Services                                  13,440            12,434               1,006                     8  %            42,647            26,497              16,150                    61  %
License and subscriptions                    463             6,350              (5,887)                  (93) %               913            13,020             (12,107)                  (93) %
Products                                   6,264             8,461              (2,197)                  (26) %            18,550            14,104               4,446                    32  %
Total costs of revenues                   20,167            27,245              (7,078)                  (26) %            62,110            53,621               8,489                    16  %
Gross profit                              18,499            17,947                 552                     3  %            56,196            36,269              19,927                    55  %
Operating expenses:
Sales and marketing                        4,771             3,090               1,681                    54  %            10,983             5,670               5,313                    94  %
Research and development                   2,231             1,916                 315                    16  %             5,600             5,759                (159)                   (3) %
General and administrative                13,922            11,452               2,470                    22  %            42,213            22,481              19,732                    88  %
Depreciation and amortization              3,336             3,626                (290)                   (8) %            13,272             7,496               5,776                    77  %
Stock-based compensation                   2,126               410               1,716                   419  %             4,588               410               4,178                 1,019  %
Lease abandonment expenses                     -               915                (915)                 (100) %                75               915                (840)                  (92) %
Goodwill and intangible asset
impairment                               106,096                 -             106,096                     -  %           112,270                 -             112,270                     -  %
Acquisition, integration, and
transformation costs                       6,049             1,227               4,822                   393  %            15,182            36,566             (21,384)                  (58) %
Total operating expenses                 138,531            22,636             115,895                   512  %           204,183            79,297             124,886                   157  %
Loss from operations                    (120,032)           (4,689)           (115,343)                2,460  %          (147,987)          (43,028)           (104,959)                  244  %
Other income (expense):
Interest expense                          (6,708)           (8,145)              1,437                   (18) %           (20,306)          (13,760)             (6,546)                   48  %
Gain on consolidation of equity
investment                                     -                 -                   -                     -  %                 -               640                (640)                 (100) %
Loss on deconsolidation of
subsidiary                               (37,708)                -             (37,708)                    -  %           (37,708)                -             (37,708)                    -  %
Gain on fair value of derivative
liability                                    223            49,885             (49,662)                 (100) %             6,893            49,885             (42,992)                  (86) %
Gain on fair value of warrant
liabilities                                    -               373                (373)                 (100) %               190             1,447              (1,257)                  (87) %
Gain (loss) on extinguishment of
debt                                     (14,610)                -             (14,610)                    -  %           (14,610)              151             (14,761)               (9,775) %
Other income, net, including
interest income                               32               259                (227)                  (88) %                30                40                 (10)                  (25) %
Total other income (expense)             (58,771)           42,372            (101,143)                 (239) %           (65,511)           38,403            (103,914)                 (271) %
Income (loss) before income tax
benefit (expense)                       (178,803)           37,683            (216,486)                 (574) %          (213,498)           (4,625)           (208,873)                4,516  %
Income tax benefit (expense)              13,219            (6,695)             19,914                  (297) %            17,744               357              17,387                 4,870  %
Net income (loss) before loss from
equity investment                       (165,584)           30,988            (196,572)                 (634) %          (195,754)           (4,268)           (191,486)                4,487  %
Loss from equity investment                    -                 -                   -                     -  %                 -              (561)                561                  (100) %
Net income (loss)                       (165,584)           30,988            (196,572)                 (634) %          (195,754)           (4,829)           (190,925)                3,954  %
Less: net income (loss) attributable
to noncontrolling interests                  178               231                 (53)                  (23) %              (109)              147                (256)                 (174) %
Net income (loss) attributable to
UpHealth, Inc.                       $  (165,762)         $ 30,757          $ (196,519)                 (639) %       $  (195,645)         $ (4,976)         $ (190,669)                3,832  %





                                       44
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The following table sets forth the consolidated results of operations of
UpHealth as a percentage of total revenue:



                                                        Three Months Ended September 30,              Nine Months Ended September 30,
                                                           2022                   2021                   2022                   2021
Revenues:
Services                                                         71  %                 49  %                   69  %                51  %
Licenses and subscriptions                                        5  %                 24  %                    9  %                26  %
Products                                                         23  %                 27  %                   22  %                23  %
Total revenues                                                  100  %                100  %                  100  %               100  %
Costs of revenues:
Services                                                         35  %                 28  %                   36  %                29  %
License and subscriptions                                         1  %                 14  %                    1  %                14  %
Products                                                         16  %                 19  %                   16  %                16  %
Total costs of revenues                                          52  %                 60  %                   52  %                60  %
Gross profit                                                     48  %                 40  %                   48  %                40  %
Operating expenses:
Sales and marketing                                              12  %                  7  %                    9  %                 6  %
Research and development                                          6  %                  4  %                    5  %                 6  %
General and administrative                                       36  %                 25  %                   36  %                25  %
Depreciation and amortization                                     9  %                  8  %                   11  %                 8  %
Stock-based compensation                                          5  %                  1  %                    4  %                 -  %
Lease abandonment expenses                                        -  %                  2  %                    -  %                 1  %
Goodwill and intangible asset impairment                        274  %                  -  %                   95  %                 -  %
Acquisition, integration, and transformation costs               16  %                  3  %                   13  %                41  %
Total operating expenses                                        358  %                 50  %                  173  %                88  %
Loss from operations                                           (310) %                (10) %                 (125) %               (48) %
Other income (expense):
Interest expense                                                (17) %                (18) %                  (17) %               (15) %
Gain on consolidation of equity investment                        -  %                  -  %                    -  %                 1  %
Loss on deconsolidation of subsidiary                           (98) %                  -  %                  (32) %                 -  %
Gain on fair value of derivative liability                        1  %                110  %                    6  %                55  %
Gain on fair value of warrant liabilities                         -  %                  1  %                    -  %                 2  %
Gain (loss) on extinguishment of debt                           (38) %                  -  %                  (12) %                 -  %
Other income, net, including interest income                      -  %                  1  %                    -  %                 -  %
Total other income (expense)                                   (152) %                 94  %                  (55) %                43  %
Income (loss) before income tax benefit (expense)              (462) %                 83  %                 (180) %                (5) %
Income tax benefit (expense)                                     34  %                (15) %                   15  %                 -  %
Net income (loss) before loss from equity
investment                                                     (428) %                 69  %                 (165) %                (5) %
Loss from equity investment                                       -  %                  -  %                    -  %                (1) %
Net income (loss)                                              (428) %                 69  %                 (165) %                (5) %
Less: net income (loss) attributable to
noncontrolling interests                                          -  %                  1  %                    -  %                 -  %
Net income (loss) attributable to UpHealth, Inc.               (429) %                 68  %                 (165) %                (6) %


Due to the timing of UpHealth's acquisitions of TTC, Glocal, Innovations Group,
and Cloudbreak, and the deconsolidation of Glocal during the third quarter of
2022, the numbers presented above are not directly comparable between periods.

Three months ended September 30, 2022 and 2021

Revenue


In the three months ended September 30, 2022, revenues were $38.7 million, a
decrease of $6.5 million, or 14%, compared to $45.2 million in the three months
ended September 30, 2021. Services revenues increased $5.6 million, primarily
due to a $3.6 million increase in the Virtual Care Infrastructure segment due to
increases in both new clients and additional revenues from existing clients at
Cloudbreak, partially offset by decreased revenues from the deconsolidation of
Glocal. Products revenues decreased $3.2 million, primarily resulting from the
deconsolidation of Glocal. Licenses and subscriptions revenues decreased $8.9
million, primarily due to Thrasys' loss of a contract with a European customer.
                                       45
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We expect revenues to increase in 2022 as compared to fiscal 2021 due to a full
year of operations for TTC, Innovations Group, and Cloudbreak, which were
acquired in the first half of 2021, partially offset by the deconsolidation of
Glocal. In addition, we expect revenues to increase for the foreseeable future
as we invest in advertising and marketing, as well as in the integration and
development of our technology platforms across each of our segments.

Cost of Revenues


In the three months ended September 30, 2022, cost of revenues was $20.2
million, a decrease of $7.1 million, or 26%, compared to $27.2 million in the
three months ended September 30, 2021. Cost of services increased $1.0 million,
primarily due to a $0.5 million increase in the Virtual Care Infrastructure
segment resulting from increased revenues at Cloudbreak, partially offset by the
deconsolidation of Glocal, and a $0.7 million increase in the Services segment
primarily resulting from increased compensation and contract labor costs to
support revenue growth at TTC in the three months ended September 30, 2022. Cost
of products decreased $2.2 million, primarily due to the deconsolidation of
Glocal. Cost of licenses and subscriptions declined $5.9 million, primarily due
to Thrasys' loss of a contract with a European customer.

We expect cost of revenues to increase for the foreseeable future, commensurate
with the growth in our revenue. Our cost of revenues may fluctuate as a
percentage of our total revenues (gross margin %) from period to period due to
the changes in the percentage of revenues contributed by each of our segments.
This growth will be partially offset by the deconsolidation of Glocal.

Operating Expenses


Sales and Marketing. In the three months ended September 30, 2022, S&M expenses,
which primarily consisted of advertising, marketing programs, and events,
including related wages, commissions and travel expenses, were $4.8 million,
compared to $3.1 million in the three months ended September 30, 2021. The
increase in S&M expenses was largely due to a $0.6 million increase in S&M
expenses at Thrasys for business development, a $0.5 million increase in S&M
expenses at Cloudbreak due to increased commission expenses resulting from
increased revenue, a $0.4 million increase in corporate S&M expenses related to
additional headcount, and a $0.2 million increase in S&M expenses at TTC due to
increased headcount to support new business.

We expect the rate of growth in S&M expenses to decrease for the foreseeable
future as we target investment in advertising and marketing. Our S&M expenses
may fluctuate as a percentage of our total revenues from period to period due to
the timing and extent we promote our brands through a variety of marketing and
public relations activities. This growth will be partially offset by the
deconsolidation of Glocal.

Research and Development. In the three months ended September 30, 2022, R&D
expenses, which primarily consisted of compensation and benefits expenses and
other administrative costs related to the software development teams, were $2.2
million compared to $1.9 million in the three months ended September 30, 2021.
The increase in R&D expenses was largely due to an increase in compensation and
benefits at Cloudbreak for ongoing initiatives, net of an increase in the
capitalization of internal-use software development costs.

We expect the rate of growth in R&D expense to decrease for the foreseeable
future as we target investment in the development of our technology platforms
across each of our segments. Our R&D expenses may fluctuate as a percentage of
our total revenues from period to period due to the timing and extent of our
technology and development expenses, including the ability to capitalize
internal-use software development costs. Historically, the majority of our
technology and development costs have been expensed, except those costs that
have been capitalized as internal-use software development costs.

General and Administrative. In the three months ended September 30, 2022, G&A
expenses, which primarily consisted of compensation and benefits expenses and
other administrative costs related to the executive, finance, human resources,
legal, facilities, and information technology teams, net of allocations to cost
of revenues and S&M and R&D expenses, were $13.9 million, compared to $11.5
million in the three months ended September 30, 2021. The increase in G&A
expenses of $2.4 million was largely due an increase of approximately $4.3
million in corporate expenses, primarily related to increased professional and
legal fees of $2.9 million and increased compensation and benefits of $1.9
million due to increased headcount, partially offset by a decrease of
approximately $2.1 million in the Services and Virtual Care Infrastructure
segments primarily due to reductions in headcount and decreases in professional
fees.

We expect the rate of growth in G&A expense to decrease at corporate as we build
out our executive, finance, human resources, legal, facilities, and information
technology teams, net of savings we expect to realize as we continue to
integrate and centralize G&A functions across our segments. In addition, we
expect our G&A expenses to increase for the foreseeable future as we continue to
grow our business and pursue litigation or arbitration or defend ourselves in
litigation. Our G&A expenses may fluctuate as a percentage of our total revenues
from period to period due to the timing and extent of our G&A expenses.

Depreciation and Amortization. In the three months ended September 30, 2022,
depreciation and amortization expenses were $3.3 million, primarily consisting
of $2.7 million of amortization of intangible assets and $0.6 million of
depreciation related to property, plant and equipment, net of allocations to
cost of revenues. In the three months ended September 30, 2021 depreciation and
amortization expenses were
                                       46
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$3.6 million, primarily consisting of $3.5 million of amortization of intangible
assets and $0.1 million of depreciation related to property and equipment, net
of allocations to cost of revenues. The decrease in depreciation and
amortization expenses was primarily due to the deconsolidation of Glocal,
partially offset by increased amortization related to the increased
capitalization of internal-use software development costs in the Integrated Care
Management segment and increased depreciation related to additions to property,
plant and equipment in the Services segment.

We expect depreciation and amortization expenses to increase in fiscal 2022 due
to a full year of operations for TTC, Innovations Group and Cloudbreak, which
were acquired in the first half of 2021, increased amortization related to the
increased capitalization of internal-use software development costs, and
increased depreciation related to additions to property, plant and equipment,
partially offset by the deconsolidation of Glocal.

Stock-Based Compensation. In the three months ended September 30, 2022,
stock-based compensation expenses were $2.1 million, related to grants under
equity incentive plans. In the three months ended September 30, 2021,
stock-based compensation expenses were $0.4 million, related to grants under
equity incentive plans. We expect stock-based compensation expenses to continue
to increase for the remainder of fiscal 2022 as we continue to make grants under
our equity incentive plan to new and existing employees.

Goodwill and Intangible Asset Impairment. An impairment charge of $106.1 million
was recognized in the three months ended September 30, 2022, consisting of a
$104.4 million impairment charge at Thrasys and a $1.7 million impairment charge
at BHS resulting from our impairment test performed during the three months
ended September 30, 2022 due to identified indicators of impairment. No
impairment charge was recognized in the three months ended September 30, 2021.

Acquisition, Integration and Transformation Costs. In the three months ended
September 30, 2022, acquisition, integration and transformation costs were $6.0
million, primarily related to professional fees for on-going litigation and
business transformation. In the three months ended September 30, 2021,
acquisition, integration and transformation costs were $1.2 million, primarily
consisting of one-time transaction expenses related to the acquisitions of
Thrasys, BHS, TTC, Glocal, Innovations Group, and Cloudbreak and UpHealth
Holdings' merger with UpHealth.

Other Income (Expense)


In the three months ended September 30, 2022, other expense was $58.8 million,
primarily consisting of $37.7 million due to the loss on the deconsolidation of
Glocal, $14.6 million of loss on extinguishment of debt and $6.7 million of
interest expense, partially offset by a $0.2 million of gain on fair value of
derivative liability. In the three months ended September 30, 2021, other income
was $42.4 million, primarily consisting of a $49.9 million gain on fair value of
derivative liability, $0.4 million gain on fair value of warrants and $0.3
million of other income, net, partially offset by $8.1 million of interest
expense.

Income Tax Benefit (Expense)


In the three months ended September 30, 2022, the income tax benefit was $13.2
million. In the three months ended September 30, 2021, the income tax expense
was $6.7 million.

Income tax benefit reflects management's best assessment of estimated current
and future taxes to be paid. The objectives for accounting for income taxes, as
prescribed by the relevant accounting guidance, are to recognize the amount of
taxes payable or refundable for the current year and deferred tax assets and
liabilities for future tax consequences of events that have been recognized in
our financial statements.

Nine months ended September 30, 2022 and 2021

Revenue


In the nine months ended September 30, 2022, revenues were $118.3 million, an
increase of $28.4 million, or 32%, compared to $89.9 million in the nine months
ended September 30, 2021. Services revenues increased $35.8 million, primarily
due to an increase of $29.0 million in the Virtual Care Infrastructure segment
resulting from a full period of operations in the nine months ended September
30, 2022 at Cloudbreak, which was acquired in June 2021, and increases in both
new clients and additional revenues from existing clients at Cloudbreak,
partially offset by the deconsolidation of Glocal, and an increase of $8.9
million in the Services segment resulting from a full period of operations in
the nine months ended September 30, 2022 at Innovations Group, which was
acquired in April 2021. Products revenues increased $5.7 million, primarily due
to a full period of operations in the nine months ended September 30, 2022 at
Innovations Group. Licenses and subscriptions revenues declined $13.1 million,
primarily due to Thrasys' loss of a contract with a European customer, net of
increased revenues from an amended contract with an existing customer.
                                       47
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We expect revenues to continue to increase in fiscal 2022 as compared to fiscal
2021 due to a full year of operations for TTC, Innovations Group, and
Cloudbreak, which were acquired in the first half of 2021, partially offset by
the deconsolidation of Glocal. In addition, we expect revenues to increase for
the foreseeable future as we invest in advertising and marketing, as well as in
the integration and development of our technology platforms across each of our
segments.

Cost of revenues

In the nine months ended September 30, 2022, cost of revenues was $62.1 million,
an increase of $8.5 million, or 16%, compared to $53.6 million in the nine
months ended September 30, 2021. Cost of services increased $16.2 million,
primarily due to an increase of $12.8 million in the Virtual Care Infrastructure
segment resulting from a full period of operations in the nine months ended
September 30, 2022 at Cloudbreak, which was acquired in June 2021, as well as
increases in both new clients and additional revenues from existing clients at
Cloudbreak, partially offset by the deconsolidation of Glocal, and due to an
increase of $3.4 million in the Services segment resulting from a full period of
operations in the nine months ended September 30, 2022 at Innovations Group,
which was acquired in April 2021. Cost of products increased $4.4 million,
primarily due to a full period of operations in the nine months ended September
30, 2022 at Innovations Group. Cost of licenses and subscriptions revenues
declined $12.1 million, primarily due to Thrasys' loss of a contract with a
European customer.

We expect cost of revenues to increase in fiscal 2022 as compared to fiscal 2021
due to a full year of operations for TTC, Innovations Group and Cloudbreak,
which were acquired in the first half of 2021, partially offset by the
deconsolidation of Glocal. In addition, we expect cost of revenues to increase
for the foreseeable future, commensurate with the growth in our revenue. Our
cost of revenues may fluctuate as a percentage of our total revenues (gross
margin %) from period to period due to the changes in the percentage of revenues
contributed by each of our segments.

Operating Expenses


Sales and Marketing. In the nine months ended September 30, 2022, S&M expenses,
which primarily consisted of advertising, marketing programs, and events,
including related wages, commissions and travel expenses, were $11.0 million,
compared to $5.7 million in the nine months ended September 30, 2021. The
increase in S&M expenses was largely due to a full period of operations in the
nine months ended September 30, 2022 for Innovations Group and Cloudbreak, which
were acquired in the second quarter of 2021, as well as TTC, which was acquired
in the first quarter of 2021, partially offset by the deconsolidation of Glocal.

We expect S&M expenses to increase in fiscal 2022 as compared to fiscal 2021 due
to a full year of operations for TTC, Innovations Group and Cloudbreak, which
were acquired in the first half of 2021, partially offset by the deconsolidation
of Glocal. In addition, we expect our S&M expenses to increase for the
foreseeable future as we invest in advertising and marketing. Our S&M expenses
may fluctuate as a percentage of our total revenues from period to period due to
the timing and extent we promote our brands through a variety of marketing and
public relations activities.

Research and Development. In the nine months ended September 30, 2022, R&D
expenses, which primarily consisted of compensation and benefits expenses and
other administrative costs related to the Thrasys' software development teams,
were $5.6 million compared to $5.8 million in the nine months ended September
30, 2021. The decrease in R&D expenses was largely due to an increase in the
capitalization of internal-use software development costs.

We expect R&D expenses to increase in fiscal 2022 as compared to fiscal 2021,
and for the foreseeable future, as we continue to invest in the development and
integration of our technology platforms across each of our segments. Our R&D
expenses may fluctuate as a percentage of our total revenues from period to
period due to the timing and extent of our technology and development expenses,
including the ability to capitalize internal-use software development costs.
Historically, the majority of our technology and development costs have been
expensed, except those costs that have been capitalized as internal-use software
development costs.

General and Administrative. In the nine months ended September 30, 2022, G&A
expenses, which primarily consisted of compensation and benefits expenses and
other administrative costs related to the executive, finance, human resources,
legal, facilities, and information technology teams, net of allocations to cost
of revenues and S&M and R&D expenses, were $42.2 million, compared to $22.5
million in the nine months ended September 30, 2021. The increase in G&A
expenses of $19.7 million was largely due an increase of approximately $12.0
million in corporate expenses, primarily related to increased professional and
legal fees and increased compensation and benefits due to increased headcount,
and to a lesser extent, a full period of operations in the nine months ended
September 30, 2022 for Innovations Group and Cloudbreak, which were acquired in
the second quarter of 2021, as well as TTC and Glocal, which were acquired in
the first quarter of 2021.

We expect G&A expenses to increase in fiscal 2022 as compared to fiscal 2021 due
to a full year of operations for TTC, Innovations Group and Cloudbreak, which
were acquired in the first half of 2021, partially offset by the deconsolidation
of Glocal, and an increase in expenses at corporate as we build out our
executive, finance, human resources, legal, facilities, and information
technology teams, net of savings we expect to realize as we continue to
integrate and centralize G&A functions across our segments. In addition, we
expect our G&A expenses to
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increase for the foreseeable future as we continue to grow our business and
pursue litigation or arbitration or defend ourselves in litigation. Our G&A
expenses may fluctuate as a percentage of our total revenues from period to
period due to the timing and extent of our G&A expenses.


Depreciation and Amortization. In the nine months ended September 30, 2022,
depreciation and amortization expenses were $13.3 million, primarily consisting
of $12.0 million of amortization of intangible assets and $2.5 million of
depreciation related to property and equipment, net of allocations to cost of
revenues. In the nine months ended September 30, 2021 depreciation and
amortization expenses were $7.5 million, primarily consisting of $7.0 million of
amortization of intangible assets and $0.5 million of depreciation related to
property and equipment, net of allocations to cost of revenues. The increase in
depreciation and amortization expenses was largely due to a full period of
amortization expense related to intangible assets in the nine months ended
September 30, 2022 for Innovations Group and Cloudbreak, which were acquired in
the second quarter of 2021, as well as TTC and Glocal, which were acquired in
the first quarter of 2021, net of the deconsolidation of Glocal, as well as
increased amortization expense related to the increased capitalization of
internal-use software development costs in the Integrated Care Management
segment and increased depreciation related to additions to property, plant and
equipment in the Services segment.

We expect depreciation and amortization expenses to increase in fiscal 2022 due
to a full year of operations for TTC, Innovations Group and Cloudbreak, which
were acquired in the first half of 2021, increased amortization related to the
increased capitalization of internal-use software development costs, and
increased depreciation related to additions to property, plant and equipment,
partially offset by the deconsolidation of Glocal.

Stock-Based Compensation. In the nine months ended September 30, 2022,
stock-based compensation expenses were $4.6 million, related to grants under
equity incentive plans. In the nine months ended September 30, 2021, stock-based
compensation expenses were $0.4 million, related to grants under equity
incentive plans. We expect stock-based compensation expenses to continue to
increase in fiscal 2022 as we continue to make grants under our equity incentive
plan to new and existing employees.

Lease Abandonment Expenses. In the nine months ended September 30, 2022, we
recorded a lease abandonment accrual in the amount of $0.1 million related to
office spaces we vacated during the period. In the nine months ended September
30, 2021, we recorded a lease abandonment accrual in the amount of $0.9 million
related to office spaces we vacated during the period.

Goodwill and Intangible Asset Impairment. In the nine months ended September 30,
2022, we recorded a goodwill and intangible asset impairment of $112.3 million,
primarily consisting of an $104.4 million impairment charge at Thrasys and a
$1.7 million impairment charge at BHS, resulting from our impairment test
performed during the three months ended September 30, 2022 due to identified
indicators of impairment, as well as a $5.5 million measurement period
adjustment at Glocal that was immediately impaired, and a $17.6 million trade
name intangible asset impairment at TTC during the three months ended March 31,
2022. No impairment charge was recognized in the nine months ended September 30,
2021.

Acquisition, Integration and Transformation Costs. In the nine months ended
September 30, 2022, acquisition, integration and transformation costs were $15.2
million, primarily consisting of consulting, legal, and severance costs incurred
to integrate and transform the businesses. In the nine months ended September
30, 2021, acquisition, integration and transformation costs were $36.6 million,
primarily consisting of one-time transaction expenses related to the
acquisitions of Thrasys, BHS, TTC, Glocal, Innovations Group, and Cloudbreak and
UpHealth Holdings' merger with UpHealth.

Other Income (Expense)


In the nine months ended September 30, 2022, other expense was $65.5 million,
primarily consisting of the loss of $37.7 million due to the deconsolidation of
Glocal, $20.3 million of interest expense and $14.6 million of loss on
extinguishment of debt, partially offset by a $6.9 million of gain on fair value
of derivative liability and a $0.2 million gain on fair value of warrant
liabilities. In the nine months ended September 30, 2021, other income was $38.4
million, primarily consisting of a $49.9 million gain on fair value of
derivative liability, a $1.4 million gain on fair value of warrant liabilities,
a $0.6 million gain on consolidation of equity investment and a $0.2 million
gain on extinguishment of debt, partially offset by $13.8 million of interest
expense.

Income Tax Benefit

In the nine months ended September 30, 2022, the income tax benefit was $17.7
million. In the nine months ended September 30, 2021, the income tax benefit was
$0.4 million.

Income tax benefit reflects management's best assessment of estimated current
and future taxes to be paid. The objectives for accounting for income taxes, as
prescribed by the relevant accounting guidance, are to recognize the amount of
taxes payable or refundable for the current year and deferred tax assets and
liabilities for future tax consequences of events that have been recognized in
our financial statements.
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Segment Information

We evaluate performance based on several factors, of which revenues and gross
profit by operating segment are the primary financial measures.

Revenues

Revenues by segment consisted of the following:

                                                            Three Months Ended September
                                                                        30,                     Nine Months Ended September 30,
In thousands                                                   2022              2021               2022               2021
Integrated Care Management                                 $   3,795          $ 11,858          $   14,230          $ 29,427
Virtual Care Infrastructure(1)                                14,978            15,284              47,423            22,838
Services                                                      19,893            18,050              56,653            37,625
Total revenues                                             $  38,666          $ 45,192          $  118,306          $ 89,890


Three Months Ended September 30, 2022 and 2021. Revenues from the Virtual Care
Infrastructure segment decreased $0.3 million, due to the deconsolidation of
Glocal in the three months ended September 30, 2022, partially offset by
increases in both new clients and additional revenues from existing clients at
Cloudbreak. Revenues from the Services segment increased $1.8 million, primarily
due to increased services from an existing client at TTC and increased revenues
at Innovations Group resulting from adding new patients and providers and
heightened conference attendance compared to the three months ended September
30, 2021, partially offset by a reduction in the number of billable encounters
and prescription volumes at BHS. Revenues from the Integrated Care Management
segment decreased $8.1 million, primarily due to Thrasys' loss of a contract
with a European customer.

Nine Months Ended September 30, 2022 and 2021. Revenues from the Virtual Care
Infrastructure segment increased $24.6 million, primarily resulting from a full
period of operations in the nine months ended September 30, 2022 at Cloudbreak,
which was acquired in June 2021, as well as increases in both new clients and
additional revenues from existing clients at Cloudbreak, partially offset by the
deconsolidation of Glocal. Revenues from the Services segment increased $19.0
million, primarily due to a full year of operations at Innovations Group and
TTC, which were acquired in the first half of 2021. Revenues from the Integrated
Care Management segment decreased $15.2 million, primarily due to Thrasys' loss
of a contract with a European customer, net of increased revenues from an
amended contract with an existing customer.

Gross profit

Gross profit by segment consisted of the following:

                                                     Three Months Ended September         Nine Months Ended September
                                                                 30,                                  30,
In thousands                                            2022              2021               2022              2021
Integrated Care Management                          $   2,854          $  4,760          $  11,385          $ 14,483
Virtual Care Infrastructure (1)                         8,191             5,838             23,779             8,771
Services                                                7,454             7,349             21,032            13,015
Total gross profit                                  $  18,499          $ 17,947          $  56,196          $ 36,269


Three Months Ended September 30, 2022 and 2021. Gross profit from the Virtual
Care Infrastructure segment increased $2.4 million, primarily due to increased
revenues at Cloudbreak resulting from increases in both new clients and
additional revenues from existing clients, partially offset by the
deconsolidation of Glocal. Gross profit from the Services segment decreased $0.1
million. Gross profit from the Integrated Care Management segment decreased $1.9
million, primarily due to Thrasys' loss of a contract with a European customer.

Nine Months Ended September 30, 2022 and 2021. Gross profit from the Virtual
Care Infrastructure segment increased $15.0 million, primarily due to a full
period of operations in the nine months ended September 30, 2022 at Cloudbreak,
which was acquired in June 2021, as well as increases in both new clients and
additional revenues from existing clients at Cloudbreak, partially offset by the
deconsolidation of Glocal. Gross profit from the Services segment increased $8.0
million, primarily due to a full period of operations in the nine months ended
September 30, 2022 at Innovations Group and TTC, which were acquired in the
first half of 2021. Gross profit from the Integrated Care Management segment
decreased $3.1 million, primarily due to Thrasys' loss of a contract with a
European customer, net of increased revenues with minimal cost from an amended
contract with an existing customer.

Liquidity and Capital Resources

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As of September 30, 2022 and December 31, 2021, we had free cash on hand of
$22.6 million and $58.2 million, respectively. Excluded from free cash on hand
as of September 30, 2022, was $7.0 million in funds held in a designated "Share
Account" maintained with a leading bank in India in the name of Glocal for which
our Chief Financial Officer is the sole authorized signatory. As of
September 30, 2022, we had no restricted cash. As of December 31, 2021, we had
restricted cash of $18.6 million, representing $18.1 million of funds held in an
escrow account as agreed in a forward share purchase agreement (see Note 10,
Capital Structure, in the Notes to Condensed Consolidated Financial Statements
of this Quarterly Report for further information) and $0.5 million of funds held
at our Glocal business.

We believe our current cash, restricted cash, and expected cash collections will
be sufficient to fund our operations for at least twelve months after the filing
date of this Quarterly Report on Form 10-Q.

Cash Flows

The following tables summarize cash flows for the nine months ended
September 30, 2022 and 2021 (unaudited):


                                                                      Nine Months Ended September 30,
(In thousands)                                                          2022                    2021
Net cash used in operating activities                            $        (17,551)         $    (48,409)
Net cash (used in) provided by investing activities                       (13,995)                2,637
Net cash (used in) provided by financing activities                       (22,188)              112,522

Effect of exchange rate changes on cash, cash equivalents, and
restricted cash

                                                              (459)                 (807)

Net (decrease) increase in cash, cash equivalents, and
restricted cash

                                                  $        (54,193)               65,943


As UpHealth’s subsidiaries are included from their dates of acquisition, as
described above, the numbers presented above are not directly comparable between
periods.


In the nine months ended September 30, 2022, cash used in operating activities
was $17.6 million, primarily attributed to the net loss of $195.8 million,
partially offset by $172.0 million of net non-cash items (loss on
deconsolidation of Glocal, depreciation, intangible amortization, loss on
extinguishment of debt, debt issuance cost amortization, impairments, and
stock-based compensation) and the changes in operating assets and liabilities,
net of effects of acquisitions, of $6.2 million. The changes in operating assets
and liabilities, net of effects of acquisitions, was primarily due to an
increase in accounts payable and accrued expenses of $10.5 million due to
delayed payments to vendors, partially offset by an increase in accounts
receivable of $5.2 million due to net aging of receivables. In the nine months
ended September 30, 2021, cash used in operating activities was $48.4 million,
primarily attributed to the net loss of $4.8 million and the changes in
operating assets and liabilities, net of effects of acquisitions, of $6.7
million, partially offset by $36.9 million of non-cash items (depreciation,
deferred tax adjustments, gain on extinguishment of debt, loss on fair value of
warrant liabilities, and debt issuance cost amortization). The changes in
operating assets and liabilities, net of effects of acquisitions, was primarily
due to an increase in accounts receivable of $27.6 million due to billed and
unbilled receivables from two customers during the quarter that were not
collected as of June 30, 2021, partially offset by an increase in accounts
payable and accrued expenses of $16.5 million due to delayed payments to
vendors.

In the nine months ended September 30, 2022, cash used in investing activities
was $14.0 million, primarily consisting of purchases of property and equipment
and capitalization of internal-use software development costs. In the nine
months ended September 30, 2021, cash provided by investing activities was $2.6
million, primarily consisting of net cash acquired in acquisition of businesses.

In the nine months ended September 30, 2022, cash used in financing activities
was $22.2 million, primarily consisting of repayments of debt obligations of
$48.2 million, repayments of seller notes of $18.7 million, the repayment of the
forward share purchase of $18.5 million and payments of capital lease
obligations of $2.5 million, partially offset by proceeds from convertible debt
of $67.5 million. In the nine months ended September 30, 2021, cash provided by
financing activities was $112.5 million, primarily consisting of proceeds from
convertible debt of $164.5 million and proceeds from merger and recapitalization
transaction of $83.4 million, partially offset by repayments of seller notes of
$99.2 million, repayments of debt of $23.3 million and payments of amounts due
to members of $4.3 million.

Debt

See Note 8, Debt, in the Notes to Condensed Consolidated Financial Statements of
this Quarterly Report for our debt.


On August 12, 2022, we entered into an indenture (the "2025 Indenture") with the
Indenture Trustee in its capacity as trustee thereunder, in respect of the
$67.5 million in aggregate principal amount of a new series of variable rate
convertible senior secured notes due December 15, 2025 (the "2025 Notes") issued
to holders of our 2026 Notes in a private placement transaction ("2025 Notes
Offering"), raising approximately $22.5 million in gross cash proceeds, net of
debt issuance costs of $2.2 million, after paying for a repurchase of
$45.0 million of the 2026 Notes, which net proceeds were used in part to fully
repay the Seller Notes. The 2025 Notes are convertible following the reverse
stock split of our shares into 3,857,142 shares of UpHealth common stock at a
conversion price, subject to the occurrence of certain corporate events, of
$17.50 per share. The 2025 Notes are senior secured obligations of UpHealth,
secured by substantially all of our assets and those of our
                                       51
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domestic subsidiaries, and accrue interest at a rate equal to the daily secured
overnight financing rate ("SOFR") plus 9.0% per annum, with a minimum rate of
10.5% per annum, payable quarterly in arrears, for a quarterly rate of 12.21%
for our December 15, 2022 interest payment date. The 2025 Notes will mature on
December 15, 2025, unless earlier repurchased, redeemed or converted. Holders
will have the right to convert their 2025 Notes at any time. Upon the occurrence
of certain corporate events, holders of the 2025 Notes can require UpHealth to
repurchase for cash all or part of their 2025 Notes in principal amounts of
$1,000 or an integral multiple thereof at a repurchase price that will be equal
to 105% of the principal amount of the 2025 Notes to be repurchased, plus
accrued and unpaid interest thereon, if any. In the event that UpHealth sells
assets with net proceeds in excess of $15.0 million, then it will make an offer
to all holders of the 2025 Notes to repurchase the 2025 Notes for an aggregate
amount of cash equal to 20.0% of the net proceeds of such asset sale, at a
repurchase price per 2025 Note equal to 100.0% of the principal amount thereof,
plus accrued and unpaid interest, if any. UpHealth may not otherwise seek to
redeem the 2025 Notes prior to June 16, 2024. UpHealth will settle conversions
solely in shares of its common stock, except for payments of cash in lieu of
fractional shares.

In December 2022, the Indenture Trustee, in its capacity as calculation agent,
notified us of the quarterly rate reset of 13.53% for our March 15, 2023
interest payment date.

Contractual Obligations and Commitments


See Note 11, Commitments and Contingencies, in the Notes to Condensed
Consolidated Financial Statements of this Quarterly Report for information about
our operating lease obligations and our non-cancellable contractual service and
licensing obligations.

Off-Balance Sheet Arrangements

As of September 30, 2022, we have not entered into any off-balance sheet
financing arrangements, established any additional special purpose entities,
guaranteed any debt or commitments of other entities, or purchased any
non-financial assets.

Recent Accounting Pronouncements

See Note 2, Summary of Significant Accounting Policies, in the Notes to
Condensed Consolidated Financial Statements of this Quarterly Report for the
recently issued accounting standards that could have an effect on us.

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